The following three papers focus on compassion, an issue well worth our consideration in our contemporary age, and most especially during our recent national tragedy. It is hoped that these philosophical discussions of compassion may help us as we, on personal and societal levels, come to grips with immense human suffering. The topic of compassion brings us into an exploration of a cluster of related philosophical issues and is thus a good stepping off point for inquiry. The role of the (...) first paper is that of stage setting, to simply layout an approach to compassion presented by Aristotle and developed by Martha Nussbaum. This approach served as the introductory consideration in a course on compassion, taught by the first two commentators. Initially we wondered if we could sustain discussion on this narrow topic over fourteen weeks, but found the course left students with numerous questions worth their further consideration. So too in these papers, a number of issues will remain untouched, such as the relation of compassion and public policy and specific approaches to the cultivating of compassion, both of which are explored at length by Martha Nussbaum. This first paper frames our discussion, by presenting in outline form key points addressed in Martha Nussbaum’s Aristotelian discussion of the emotion of compassion, and touches upon issues developed in the next two papers. (shrink)

The following three papers focus on compassion, an issue well worth our consideration in our contemporary age, and most especially during our recent national tragedy. It is hoped that these philosophical discussions of compassion may help us as we, on personal and societal levels, come to grips with immense human suffering. The topic of compassion brings us into an exploration of a cluster of related philosophical issues and is thus a good stepping off point for inquiry. The role of the (...) first paper is that of stage setting, to simply layout an approach to compassion presented by Aristotle and developed by Martha Nussbaum. This approach served as the introductory consideration in a course on compassion, taught by the first two commentators. Initially we wondered if we could sustain discussion on this narrow topic over fourteen weeks, but found the course left students with numerous questions worth their further consideration. So too in these papers, a number of issues will remain untouched, such as the relation of compassion and public policy and specific approaches to the cultivating of compassion, both of which are explored at length by Martha Nussbaum. This first paper frames our discussion, by presenting in outline form key points addressed in Martha Nussbaum’s Aristotelian discussion of the emotion of compassion, and touches upon issues developed in the next two papers. (shrink)

This article considers the relation between tolerance and hospitality. It situates this discussion in the history of philosophy with reference to a range of thinkers from Homer and Aristotle to Levinas, Derrida, and Walzer. It argues that the virtue of hospitality is important for negotiating the complexities of our contemporary world. Hospitality responds to the challenge of what is most needed for re-conceiving how one might remain committed to the values of one's own community while also remaining open to those (...) who do not share these same commitments. (shrink)

Most characters that distinguish one individual from another, like height or weight, vary continuously in populations. Continuous variation of these ‘quantitative’ traits is due to the simultaneous segregation of multiple quantitative trait loci (QTLs) as well as environmental influences. A major challenge in human medicine, animal and plant breeding and evolutionary genetics is to identify QTLs and determine their genetic properties. Studies of the classic quantitative traits, abdominal and sternopleural bristle numbers of Drosophila, have shown that: (1) many loci have (...) small effects on bristle number, but a few have large effects and cause most of the genetic variation; (2) ‘candidate’ loci involved in bristle development often have large quantitative effects on bristle number; and (3) alleles at QTLs affecting bristle number have variable degrees of dominance, interact with each other, and affect other quantitative traits, including fitness. Lessons learned from this model system will be applicable to studies of the genetic basis of quantitative variation in other species. (shrink)

IX. 6. 12. iacere indolem illam Romanam ablatosque cum armis animos; non reddere salutem, non salutantibus dare responsum, non hiscere quemquam prae metu potuisse.

IX. 6. 12. (The young nobles of Capua describe the bearing of the Romans released from the Caudine Forks after having passed under the yoke.).

X. 13. 10, with X. 33. 3. Et ille quidem in recusando perstabat: quid ergo attineret leges ferri rogitans quibus per eosdem, qui tulissent, fraus fieret; iam regi leges non regere.

Background: The factors influencing parents’ willingness to enroll their children in biobanks are poorly understood. This study sought to assess parents’ willingness to enroll their children, and their perceived benefits, concerns, and information needs under different consent and data-sharing scenarios, and to identify factors associated with willingness. Methods: This large, experimental survey of patients at the 11 eMERGE Network sites used a disproportionate stratified sampling scheme to enrich the sample with historically underrepresented groups. Participants were randomized to receive one of (...) three consent and data-sharing scenarios. Results: In total, 90,000 surveys were mailed and 13,000 individuals responded (15.8% response rate). 5737 respondents were parents of minor children. Overall, 55% (95% confidence interval 50–59%) of parents were willing to enroll their youngest minor child in a hypothetical biobank; willingness did not differ between consent and data-sharing scenarios. Lower educational attainment, higher religiosity, lower trust, worries about privacy, and attitudes about benefits, concerns, and information needs were independently associated with less willingness to allow their child to participate. Of parents who were willing to participate themselves, 25% were not willing to allow their child to participate. Being willing to participate but not willing to allow one’s child to participate was independently associated with multiple factors, including race, lower educational attainment, lower annual household income, public health care insurance, and higher religiosity. Conclusions: Fifty-five percent of parents were willing to allow their youngest minor child to participate in a hypothetical biobank. Building trust, protecting privacy, and addressing attitudes may increase enrollment and diversity in pediatric biobanks. (shrink)

This study explored the furry identity. Furries are humans interested in anthropomorphic art and cartoons. Some furries have zoomorphic tendencies. Furries often identify with, and/or assume, characteristics of a special/totem species of nonhuman animal. This research surveyed both furries and non-furry individuals attending a furry convention and a comparison group of college students . Furries commonly indicated dragons and various canine and feline species as their alternate-species identity; none reported a nonhuman-primate identity. Dichotomous responses to two key furry-identity questions produced (...) a two-by-two furry typology. These two independent dimensions are self-perception and species identity . One-quarter of the furry sample answered “yes” to both questions, placing them in the “Distorted Unattained” quadrant. This type of furry has certain characteristics paralleling gender-identity disorder. To explore this parallel, the furry typology, and the proposed construct of “Species Identity Disorder” needs further research. (shrink)

Variability in the symptom experience in patients diagnosed with chronic conditions may be related to social determinants of health (SDoH). The purpose of this critical review was to (1) summarize the existing literature on SDoH and symptom clusters (i.e., multiple, co‐occurring symptoms) in patients diagnosed with common chronic conditions, (2) evaluate current variables and measures used to represent SDoH, (3) identify gaps in the evidence base, and (4) provide recommendations for the incorporation of SDoH into future symptom cluster research. We (...) identified 118 articles including information on SDoH in chronic condition symptom cluster research. Articles primarily focused on cancer populations. Few articles had the explicit purpose of investigating relationships between SDoH and symptom clusters, and the inclusion of SDoH was often limited to variables used to describe samples. Future studies should be designed to “move beyond Table 1” in their utilization of SDoH as variables and examine relationships between SDoH and symptom clusters. Attention should be paid to the appropriateness of measures being used to collect information on SDoH, and analysis methods that estimate causal connections between variables should be considered. Research regarding the relationship of SDoH with symptom clusters in patients with chronic conditions has the potential to reveal mechanisms of symptom disparities and guide changes to alleviate these disparities. (shrink)

This study explored the furry identity. Furries are humans interested in anthropomorphic art and cartoons. Some furries have zoomorphic tendencies. Furries often identify with, and/or assume, characteristics of a special/totem species of nonhuman animal. This research surveyed both furries and non-furry individuals attending a furry convention and a comparison group of college students. Furries commonly indicated dragons and various canine and feline species as their alternate-species identity; none reported a nonhuman-primate identity. Dichotomous responses to two key furry-identity questions produced a (...) two-by-two furry typology. These two independent dimensions are self-perception and species identity. One-quarter of the furry sample answered “yes” to both questions, placing them in the “Distorted Unattained” quadrant. This type of furry has certain characteristics paralleling gender-identity disorder. To explore this parallel, the furry typology, and the proposed construct of “Species Identity Disorder” needs further research. (shrink)

During the last twelvemonth we have been engaged in finally preparing for press the first volume of our text of Livy in the Bibliotheca Classica Oxoniensis, and we now desire to submit beforehand to the judgement of scholars some of the chief alterations in the current text that we have been led to adopt. It will be seen that some proportion of them consist of little more than a defence of the MS tradition; and where we have proposed changes of (...) our own, we have, we believe, rigorously confined ourselves not merely to such suggestions as can be readily reconciled with the reading of at least one good manuscript, but to such as provide in each case a tenable explanation of the origin of all the variants in all the MSS that we have consulted. In several difficult places we have become persuaded that corruption has arisen through slight and accountable dislocations of order, and in a still larger number from the incorporation of marginal or interlinear glosses not differing in character from those which still appear in great numbers in all the MSS of the 9th to the 12th centuries, but which have not forced their way into the text. A typical example will be found in our note on V. 2. 8. (shrink)

Restitere primo obstinatis animis; deinde ut obtinentes locum †uires ferebant† audent ultro gradum inferre.

This article explores and offers a qualified defence of the claim that the entitlement to forgive a wrongdoer belongs to the victim of the wrong. A summary account of forgiveness is given, followed by arguments in favor of the victim's prerogative to forgive. Primary, or direct victims are then distinguished from secondary and tertiary ones, which point to a plurality of prerogatives to forgive. In cases of conflicts between these prerogatives it is emphasized that special care should be taken to (...) protect the primary victim's entitlement, without giving an absolute and exclusive status to the latter prerogative. Grounds for limiting the primary victim's prerogative regarding forgiveness include (a) cases where harm to secondary and/or tertiary victims are greater than the harm resulting from the original wrong committed against the primary victim, (b) the social dimensions of the elements of forgiveness, and (c) the need for self-forgiveness when a repentant wrongdoer is not forgiven by any of the victims. The practical significance of these arguments are illustrated by considering the criticism that the South African Truth and Reconciliation Commission have forgiven perpetrators in ways that inappropriately pre-empted the primary victims' entitlement to forgive. S. Afr. J. Philos. Vol.21(2) 2002: 97-111. (shrink)

The early evolution of metazoans is a major focus of biological attention, but is the historical record revealed in the Cambrian “explosion” an accurate reflection of original events? The key questions concern the nature of the earliest animals and when they originated. One widely-mooted suggestion is that planktotrophic larvae, typified by the annelidan trochophore and echinoid pluteus, existed long before the metazoan radiations evident in the Cambrian fossil record. This idea could be consistent for recent evidence of divergence times, based (...) on molecular “clocks,” of phyla appearing well before the Cambrian. Now a surprising new discovery of eggs with blastomeres and embryos with well-defined anatomy from the Cambrian (c.530 Myr ago) of China and Siberia promises to extend the arena of debate. In one case a convincing ontogeny can be traced from eggs to adult tube-dwelling cnidarians. In the other example a possible protostome, unhatched and wrapped around the egg, shows segmentation and possibly nascent sclerites. In both, these cases development is direct, i.e., there is no evidence for any planktotrophic larval stage. The implications for our perceptions of both the Cambrian ‘explosion’ and metazoan phylogeny could be considerable. BioEssays 20:676–682, 1998.© 1998 John Wiley & Sons Inc. (shrink)

The almost simultaneous and overlapping discoveries of Mendel's forgotten work by Hugo de Vries, Carl Correns, and Erik von Tschermak gave rise to an intense rivalry, some jealousy, and more than a little illfeeling. De Vries, the first to announce the discovery, has been subjected to the charge that he wished to conceal his discovery and to obtain for himself the credit for having discovered what we now call Mendelism. This charge involves the statement that de Vries gave credit to (...) Mendel only after he had found that others had also read Mendel's papers. The evidence on which this charge is based is sketchy, and we can now show that at least that portion of it that is based on supposed alteration in the proof of de Vries' paper in the Berichte is without foundation. Unfortunately, de Vries gave three different accounts of how he was led to Mendel's work. Two of these involve Liberty Hyde Bailey.Bailey had listed Mendel's papers in a bibliography that he published in 1892 in The Rural Library. Bailey did not include this bibliography in the first edition (1895) of Plant Breeding or in its reprinting in 1896 and 1897. He did include the bibliography in the second edition (1902), but this was after de Vries and others had called attention to Mendel. In 1899, both Bailey and de Vries gave papers at the Hybrid Conference held at Chiswick, England, but we have no record of their having discussed Mendel. What evidence we have indicates that, at this time, neither of them had read Mendel's papers.De Vries wrote to Bailey that it was Bailey's listing of Mendel in the bibliography published in The Rural Library that led to his discovery of Mendel. Later, de Vries wrote to H. F. Roberts that he had first found a reference to Mendel in Bailey's Plant Breeding of 1895, where the bibliographic reference to Mendel's papers was not published. Finally, de Vries told Th. J. Stomps, who succeeded him at the University of Amsterdam, that he had first learned of Mendel early in 1900 from a reprint of Mendel's paper sent him by his friend Professor M. W. Beyerinck. Our present evidence favors Stomp's account as it shows that de Vries had not read Mendel's papers in 1899 but had early in 1900.Attempts to pinpoint de Vries' discovery of Mendel are aided in part, and in part confused, by the fact that he published five relevant papers in 1900. These papers were in press simultaneously, and some of them were altered in proof. Further confusion is due to the fact that at least three of them were published in the reverse order of their acceptance for publication. Unfortunately we do not have the crucial dates for all of the papers.J. Roy. Hort. Soc. 24: 69–75. A definitely pre-Mendelian paper given on 11 July 1899, and published in 1900 (possibly in April). The evidence for an alteration in proof after de Vries had read Mendel is shown by the fact that de Vries described a ratio of 99 to 54 as a 3 to 1 ratio.Rev. gén. botan. 12: 129–137. A Mendelian paper, giving the 3 to 1 ratio in the F2 generation of a cross between starchy and sugary corn. The paper is not dated by de Vries but it was published in the volume, 128 pages ahead of a paper de Vries dated 19 March. In a footnote, de Vries cites a paper by Correns that was published on 25 January, so we can tell that it was written or corrected in proof after this date. Here Correns showed de Vries that he had already read Mendel's paper. Any attempt by de Vries to ignore Mendel or get credit for Mendelism after 25 January would have been senseless. This date was nearly two months before de Vries' Berichte paper was submitted for publication.Ber. deut. botan. Ges. 18: 83–90. Accepted for publication 14 march, published 25 April. This paper gives Mendel full credit and stimulated the publications of Correns and von Tschermak. As de Vries was aware that Correns already knew of Mendel when the paper was first submitted, there was no occasion to alter it in proof.Rev. gén. botan. 12: 257–271. Dated by de Vries 19 March, but the proof was read after June. De Vries cites von Tschermak's paper in the Berichte that was published in June. The Revue paper is a Mendelian paper, and Mendel is cited on the last page.C. R. Acad. Sci. (Paris) 130: 845–847. Accepted for publication 26 March 1900. Reprint received by Correns 21 April. Mendel is not mentioned but de Vries' use of terms told Correns that de Vries had read Mendel's paper. First of the papers to be published, it caused Correns to assume that de Vries wanted the credit that was due Mendel.The three discoverers of Mendel did not form a mutual admiration society. (shrink)

Charles Murray describes himself as a libertarian, most notably in his short book, What it Means to be a Libertarian. He might more accurately have described himself as having libertarian tendencies. My reading of Simple Justice is that the views it espouses are far more traditionalist than libertarian. Neither traditionalist state-retribution nor modernist state-leniency is libertarian. Nor does either provide as just or efficient a response to crime as does libertarian restitution, including restitutive retribution. Here, I shall respond directly only (...) to Murray's views, rather than also deal with state-leniency. This is because I accept Murray's thesis, without endorsing his specific arguments for it, that state-leniency is disastrous as a response to crimes against persons and their justly acquired property. (shrink)

Charles Murray describes himself as a libertarian, most notably in his short book, What it Means to be a Libertarian. He might more accurately have described himself as having libertarian tendencies. My reading of Simple Justice is that the views it espouses are far more traditionalist than libertarian. Neither traditionalist state-retribution nor modernist state-leniency is libertarian. Nor does either provide as just or efficient a response to crime as does libertarian restitution, including restitutive retribution. Here, I shall respond directly only (...) to Murray's views, rather than also deal with state-leniency. This is because I accept Murray's thesis, without endorsing his specific arguments for it, that state-leniency is disastrous as a response to crimes against persons and their justly acquired property. (shrink)

This book has many arguments doing an excellent job of dismantling the positions of those who would have the state do considerably more than defend the national realm. Thus far, it is hard for me to fault it—which is more difficult when one is already in agreement: the ideologically opposed can often provide more useful criticisms. But, as the book‟s title indicates, it does not go all the way to anarcho-liberalism (in fact, it does not even fully embody certain basic (...) tenets of classical liberalism). And as its criticisms of anarcho-liberalism—or private-property anarchy—are those to which I am ideologically opposed, I shall mainly concentrate on those. (shrink)

In her many articles on the subject, Trudy Govier has made a substantial contribution to the recent philosophical literature on trust—not only to the discussion kindled by Annette Baier's provocative article "Trust and Anti-Trust", but to the larger, much older, low-intensity discussion among social scientists and philosophers about the relation between trust and effective government, stable social relationships, and psychological health. This book is devoted to the varieties and uses of trust in various largely non-intimate social relationships, ranging from (...) the mundane, casual, or routine interactions of daily life to international affairs. The book is primarily expository, though there are occasional passages of conceptual analysis and some criticism of the work of others. Govier says, in her Preface, that. (shrink)

In her many articles on the subject, Trudy Govier has made a substantial contribution to the recent philosophical literature on trust—not only to the discussion kindled by Annette Baier's provocative article "Trust and Anti-Trust", but to the larger, much older, low-intensity discussion among social scientists and philosophers about the relation between trust and effective government, stable social relationships, and psychological health. This book is devoted to the varieties and uses of trust in various largely non-intimate social relationships, ranging from (...) the mundane, casual, or routine interactions of daily life to international affairs. The book is primarily expository, though there are occasional passages of conceptual analysis and some criticism of the work of others. Govier says, in her Preface, that. (shrink)

### High Court rejects assisted dying challenge The High Court has rejected the latest challenge to the law on assisted dying in the UK, brought by Noel Conway. Mr Conway, a retired college lecturer, was diagnosed with motor neuron disease in 2012. Since his diagnosis, his health has deteriorated and he is dependent on ever-increasing levels of assistance with daily life, including the use of non-invasive ventilation to help him breathe. He sought a declaration from the court that (...) section 2 of the Suicide Act 1961 was incompatible with his right to a private and family life under Article 8 of the European Convention on Human Rights. As part of his case, Mr Conway submitted the outline of an alternative statutory scheme, which he argued, if implemented, would provide sufficient safeguards. He submitted that the prohibition on assisted suicide should not apply where an individual is aged 18 and over; has been diagnosed with a terminal illness and has a clinically assessed prognosis of 6 months or less to live; has the mental capacity to make the decision; makes that decision in a voluntary, clear and settled manner; and retains the ability to undertake the final act. Additionally, two doctors must confirm that the individual meets the criteria, and permission for the provision of assistance must be authorised by a High Court judge. Previous challenges to the UK law on assisted dying, including Pretty and Nicklinson, had established that section 2 of the Suicide Act does engage individual’s Article 18 rights, but that such an interference could be justified under Article 8 of the ECHR, which permits interference ‘such as is in accordance with the law and necessary in a democratic society in the interests of national security, public safety or the economic well-being of the country’. The question …. (shrink)